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Research

Reminder to Increase Participation of Latinas to RCTs
Principal Investigator
Jeanne Mandelblatt, MD, MPH
E-mail: mandelj@georgetown.edu

Funded April 2002 through the Special Populations Network developmental research projects, the goal of this pilot is to measure the effect of a non-MD communication intervention on Latina intent to participate in the STAR breast cancer prevention clinical trials. During year three, we have finished developing the research questionnaire and completed with the data collection and data entry of approximately 450 structured interviews. This instrument assesses information pertinent to the theoretical model which includes perceived susceptibility, and severity, perceived threat, and the balance of benefits and barriers. Education level, another mediating variable, was also measured. Latino women over the age of 35 who attend LACRC clinics for non-emergency appointments were included in our sample. The Health Belief Model is being used as a guide for the design, analysis, and interpretation of the data collected.

This research pilot is one of the first studies to use a theoretical framework to describe and attempt to change Latinas cancer prevention behaviors. The primary outcome variable of this pilot is the intention to participate in the STAR trial. This research tests the following hypotheses: (1) Acting as a cue to action, discussion plus brochures will increase perceived benefits thus increasing intention to participate in the STAR trial, compared to brochures alone, controlling for covariates. (2) Perceived susceptibility to breast cancer and benefits from participating in the STAR Trial will be mediated by the relationship of the participant with her clinic/providers (years of continuity), culture and acculturation.

This data provides a foundation for future RO1s that will be developed in phase III of this grant. The goal of this future project will be to increase accrual of Latinos to cancer clinical trials. In addition, the data will be used to develop tailored messages for future interventions.

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